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Symbol
Name
ID
Orc1
origin recognition complex, subunit 1
MGI:1328337
Phenotype annotations related to digestive/alimentary system
Darker colors indicate more annotations
Human Phenotypes
Gastroesophageal reflux
Disease(s) Associated with ORC1
Meier-Gorlin syndrome 1

Mouse Phenotypes
increased small intestinal crypt cell apoptosis
abnormal small intestinal crypt cell proliferation
abnormal small intestine crypts of Lieberkuhn morphology
abnormal small intestine morphology
abnormal small intestinal villus morphology
decreased small intestinal villus height
Availability Mouse Genotype
Orc1tm1.1Gle/Orc1tm1.1Gle
Tg(Cyp1a1-cre)1Dwi/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory